Granica szumu śrutowego, czyli skalowanie niepewności estymacji parametrujak 1/\sqrt{N}, gdzie N jest liczbą cząstek w układzie, jestcharakterystyczna dla układów nieskorelowanych. Celem seminarium jestzaprezentowanie, jak znając jednociałową gęstość układu i nie posiadającżadnej wiedzy o korelacjach wielociałowych, dokonać estymacji parametru zprecyzją poniżej granicy szumu śrutowego. Zostanie podany przykład, gdyparametrem tym jest względna faza pomiędzy dwoma interferującymikondensatami Bosego-Einsteina, a precyzja estymacji skaluje się jakN^{-2/3}.
Zapraszamy do Sali Dużej Teoretycznej (229), ul. Hoża 69 o godzinie 12:15

Prof. Mai Suan Li (IF PAN)
Alzheimer's, Parkinson's, Huntington's, type II diabetes, Mad Cow diseaseetc are associated with protein misfolding. In the case of Alzheimer'sdisease, common toxic species leading to this pathology are the extensivedeposits of fibrillar aggregation of amyloid peptides. Understanding thenature and mechanism of formation of amyloid fibrils plays an importantrole in finding proper treatments. Our study reveals that the fibrilgrowth is governed by the two-stage dock-lock mechanism. In the initialstage a monomer docks onto the underlying fibril, and the locking of amonomer requires a much longer time scale. After the lock stage themonomer adopts the conformation that is commensurate with the underlying lattice. Using lattice and all-atom models, we have obtained the main factors that control the fibril formation process. Namely, in agreementwith experiments, we have shown that fibril formation times of polypeptidechains are strongly correlated with hydrophobicity, Coulomb interactionand the population of the fibril-prone conformation in the monomer state.The higher this population the faster is the fibril growth process andthis dependence may be described by a single exponential function. Ourresult opens a new way to understand the fibrillogenesis of bio moleculesat the monomer level. The role of peptide inhibitors of amyloidaggregation will be briefly discussed.1. P.H. Nguyen, Mai Suan Li, G. Stock, J. E. Straub, and D. Thirumalai, Proc. Natl. Acad. Sci. USA 104, 111-116 (2007)2. Mai Suan Li, D.K. Klimov, J. E. Straub, and D. Thirumalai, J. Chem. Phys. 129, 175101 (2008).3. H. B. Nam, M. Kouza, H. Zung, and Mai Suan Li, J. Chem. Phys. 132, 165104 (2010)4. Mai Suan Li, N.T. Co, G. Reddy, C-K. Hu, and D. Thirumalai, Phys. Rev. Lett. 105, 218101 (2010).5. M.H. Viet, S.T. Ngo, N.S. Lam , and Mai Suan Li, J. Phys. Chem. B 115, 7433 (2011)
Zapraszamy do Sali Dużej Teoretycznej (229), ul. Hoża 69 o godzinie 12:15

Dr Mykola Tasinkevych (MPI for Intelligent Systems, Stuttgart)
Synthetic micro-motors which can move cargo in a well controlled waythrough a liquid environment are of signicant interest for applicationssuch as targeted drug delivery, biosensing, or shuttle-transport of livingcells. One promising approach is to use catalytically active Januscolloidal particles as model micro-motors. Due to an asymmetric decorationof their surface with a catalyst, which promotes a specic chemicalreaction in the surrounding liquid, concentration gradients of thereaction products develop along the surface of the particle. Depending onthe systems, various self-propulsion mechanisms emerge, such as bubblepropulsion, self-electrophoresis, or self-diusiophoresis. In this talk weconsider only the last mechanism, i.e. self-propulsion due toself-generated electrically neutral solute gradients. First, we discussthe self-diusiophoretic motion of a spheroidal particle, which is coveredby a catalyst over a cap-like region centered at one of the poles of theparticle. We describe how theself-phoretic velocity depends on the aspect ratio of the polar and theequatorial diameters of the particle and on the fraction of the particlesurface contributing to the chemical reaction. Next we show that suchparticles can be used as micro-carriers. As a simple model for acarrier-cargo system we consider a catalytically active particle connectedby a thin rigid rod to a catalytically inert cargo particle. We show thatthe velocity of the composite strongly depends on the relative orientationof the carrier-cargo link. Accordingly, there is an optimal congurationfor the linkage. The subtlety of such carriers is underscored by theobservation that a spherical particle completely covered by catalyst,which is motionless when isolated, acts as a carrier once attached to acargo.
Zapraszamy do Sali Dużej Teoretycznej (229), ul. Hoża 69 o godzinie 12:15

Dr Tiziana Di Matteo (King's College London, UK)
In this talk I will briefly give a broad overview of the state of the art in Econophysics: a discipline that has already a rich history and even controversial trends [1]. In particular, I will show results concerning the characterization and visualization of correlations in financial systems by means of network theory and I will introduce a new tool to filter relevant information in these systems and to extract the hierarchical structure of the market [2]. I will discuss the economic meaning of the financial market hierarchical structure and its dynamical evolution [3,4]. I will investigate the statistical signatures of the ‘credit crunch’ financial crisis that unfolded between 2008 and 2009 discussing results that show an intriguing trend that highlights a consistently decreasing centrality of the financial sector over the last 10 years [5]. I will also introduce a graph-theoretic approach to extract clusters and hierarchies in complex data- sets in an unsupervised and deterministic manner, without the use of any prior information. Applications to financial data-sets show that industrial sectors and specific activities can be extracted and meaningfully identified from the analysis of the collective fluctuations of prices in an equity market [6]. [1] "Topical Issue: Trends in Econophysics" in EPJB, Vol. 55, No. 2 (2007). [2] M. Tumminello, T. Aste, T. Di Matteo, R. N. Mantegna, PNAS 102, n. 30 (2005) 1 10421. [3] F. Pozzi, T. Di Matteo and T. Aste, Advances in Complex Systems 11 (2008) 927. [4] T. Di Matteo, F. Pozzi, T. Aste, The European Physical Journal B 73 (2010) 3-11. [5] T. Aste, W. Shaw, T. Di Matteo, New J. Phys. 12 (2010) 085009. [6] Won-Min Song, T. Di Matteo and Tomaso Aste, submitted (2011).